Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ret  ret proto-oncogene   (Synonyms: c-Ret, RET51, RET9)
Results	Reference
1*	J:82111 Allmendinger A, Stoeckel E, Saarma M, Unsicker K, Huber K, Development of adrenal chromaffin cells is largely normal in mice lacking the receptor tyrosine kinase c-Ret. Mech Dev. 2003 Mar;120(3):299-304
1	J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44
1	J:157721 Bourane S, Garces A, Venteo S, Pattyn A, Hubert T, Fichard A, Puech S, Boukhaddaoui H, Baudet C, Takahashi S, Valmier J, Carroll P, Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling. Neuron. 2009 Dec 24;64(6):857-70
1*	J:136068 Bridgewater D, Cox B, Cain J, Lau A, Athaide V, Gill PS, Kuure S, Sainio K, Rosenblum ND, Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev Biol. 2008 May 1;317(1):83-94
1	J:172032 Cain JE, Islam E, Haxho F, Blake J, Rosenblum ND, GLI3 repressor controls functional development of the mouse ureter. J Clin Invest. 2011 Mar 1;121(3):1199-206
1	J:154102 Cain JE, Islam E, Haxho F, Chen L, Bridgewater D, Nieuwenhuis E, Hui CC, Rosenblum ND, GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One. 2009;4(10):e7313
1*	J:98366 Chan KK, Chen YS, Yau TO, Fu M, Lui VC, Tam PK, Sham MH, Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development. Dev Dyn. 2005 Jun;233(2):473-83
1	J:203312 Chi L, Galtseva A, Chen L, Mo R, Hui CC, Rosenblum ND, Kif3a controls murine nephron number via GLI3 repressor, cell survival, and gene expression in a lineage-specific manner. PLoS One. 2013;8(6):e65448
1*	J:100439 Cohen S, Funkelstein L, Livet J, Rougon G, Henderson CE, Castellani V, Mann F, A semaphorin code defines subpopulations of spinal motor neurons during mouse development. Eur J Neurosci. 2005 Apr;21(7):1767-76
1	J:180432 D'Autreaux F, Coppola E, Hirsch MR, Birchmeier C, Brunet JF, Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20018-23
1	J:71588 de Graaff E, Srinivas S, Kilkenny C, D'Agati V, Mankoo BS, Costantini F, Pachnis V, Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes Dev. 2001 Sep 15;15(18):2433-44
1	J:270523 Desgrange A, Heliot C, Skovorodkin I, Akram SU, Heikkila J, Ronkainen VP, Miinalainen I, Vainio SJ, Cereghini S, HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis. Development. 2017 Dec 15;144(24):4704-4719
1	J:130616 Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM Jr, Milbrandt J, GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 2004 Nov 18;44(4):623-36
1	J:220812 Fleming MS, Vysochan A, Paixao S, Niu J, Klein R, Savitt JM, Luo W, Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors. Elife. 2015;4
1	J:63174 Garces A, Haase G, Airaksinen MS, Livet J, Filippi P, deLapeyriere O, GFRalpha 1 is required for development of distinct subpopulations of motoneuron. J Neurosci. 2000 Jul 1;20(13):4992-5000
1*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:210997 Ihermann-Hella A, Lume M, Miinalainen IJ, Pirttiniemi A, Gui Y, Peranen J, Charron J, Saarma M, Costantini F, Kuure S, Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion. PLoS Genet. 2014 Mar;10(3):e1004193
1*	J:83648 Lee KY, Samy ET, Sham MH, Tam PK, Lui VC, 3' Splicing variants of ret receptor tyrosine kinase are differentially expressed in mouse embryos and in adult mice. Biochim Biophys Acta. 2003 May 13;1627(1):26-38
1	J:157722 Luo W, Enomoto H, Rice FL, Milbrandt J, Ginty DD, Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling. Neuron. 2009 Dec 24;64(6):841-56
1	J:44407 Luukko K, Suvanto P, Saarma M, Thesleff I, Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis. Dev Dyn. 1997 Dec;210(4):463-71
1	J:81970 McCallion AS, Stames E, Conlon RA, Chakravarti A, Phenotype variation in two-locus mouse models of Hirschsprung disease: tissue-specific interaction between Ret and Ednrb. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1826-31
1*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1	J:43790 Molliver DC, Wright DE, Leitner ML, Parsadanian AS, Doster K, Wen D, Yan Q, Snider WD, IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. Neuron. 1997 Oct;19(4):849-61
1	J:39084 Morin X, Cremer H, Hirsch MR, Kapur RP, Goridis C, Brunet JF, Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Neuron. 1997 Mar;18(3):411-23
1	J:186888 Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J, Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int. 2011 Feb;79(3):317-30
1	J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9
1	J:254316 Phelep A, Laouari D, Bharti K, Burtin M, Tammaccaro S, Garbay S, Nguyen C, Vasseur F, Blanc T, Berissi S, Langa-Vives F, Fischer E, Druilhe A, Arnheiter H, Friedlander G, Pontoglio M, Terzi F, MITF - A controls branching morphogenesis and nephron endowment. PLoS Genet. 2017 Dec;13(12):e1007093
1	J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51
1	J:55785 Quaggin SE, Schwartz L, Cui S, Igarashi P, Deimling J, Post M, Rossant J, The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis. Development. 1999 Dec;126(24):5771-83
1	J:264120 Rowan CJ, Li W, Martirosyan H, Erwood S, Hu D, Kim YK, Sheybani-Deloui S, Mulder J, Blake J, Chen L, Rosenblum ND, Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFbeta signaling. Development. 2018 Jul 9;145(13):dev159947
1*	J:81008 Sato A, Matsumoto Y, Koide U, Kataoka Y, Yoshida N, Yokota T, Asashima M, Nishinakamura R, Zinc finger protein sall2 is not essential for embryonic and kidney development. Mol Cell Biol. 2003 Jan;23(1):62-9
1	J:316652 Sims-Lucas S, Di Giovanni V, Schaefer C, Cusack B, Eswarakumar VP, Bates CM, Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2alpha signaling in the metanephric mesenchyme. J Am Soc Nephrol. 2012 Apr;23(4):607-17
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:343072 Vermeiren S, Cabochette P, Dannawi M, Desiderio S, San Jose AS, Achouri Y, Kricha S, Sitte M, Salinas-Riester G, Vanhollebeke B, Brunet JF, Bellefroid EJ, Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. iScience. 2023 Dec 15;26(12):108364
1	J:73864 Wallen A A, Castro DS, Zetterstrom RH, Karlen M, Olson L, Ericson J, Perlmann T, Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem. Mol Cell Neurosci. 2001 Dec;18(6):649-63
1	J:102170 Wong A, Bogni S, Kotka P, de Graaff E, D'Agati V, Costantini F, Pachnis V, Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform. Mol Cell Biol. 2005 Nov;25(21):9661-73
1	J:176365 Yallowitz AR, Hrycaj SM, Short KM, Smyth IM, Wellik DM, Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma. PLoS One. 2011;6(8):e23410
1	J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767